Heterochromia Iridum - Classification - Acquired Heterochromia - Abnormal Iris Darker

Abnormal Iris Darker

  • Deposition of material
    • Siderosis – iron deposition within ocular tissues due to a penetrating injury and a retained iron-containing, intraocular foreign body.
    • Hemosiderosis – long standing hyphema (blood in the anterior chamber) following blunt trauma to the eye may lead to iron deposition from blood products
  • Certain eyedrops – prostaglandin analogues (latanoprost, isopropyl unoprostone, travoprost, and bimatoprost) are used topically to lower intraocular pressure in glaucoma patients. A concentric heterochromia has developed in some patients applying these drugs. The stroma around the iris sphincter muscle becomes darker than the peripheral stroma. A stimulation of melanin synthesis within iris melanocytes has been postulated.
  • Neoplasm – Nevi and melanomatous tumors.
  • Iridocorneal endothelium syndrome
  • Iris ectropion syndrome

Read more about this topic:  Heterochromia Iridum, Classification, Acquired Heterochromia

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