History
Choline was discovered by Adolph Strecker in 1864 and chemically synthesized in 1866. In 1998 choline was classified as an essential nutrient by the Food and Nutrition Board of the Institute of Medicine (USA).
Choline's importance as a nutrient was first appreciated in the early research on insulin functions when choline was found to be the necessary nutrient in preventing fatty liver. In 1975 scientists discovered that the administration of choline increased the synthesis and release of acetylcholine by neurons. These discoveries lead to the increased interest in dietary choline and brain function.
Read more about this topic: Choline
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“There is no history of how bad became better.”
—Henry David Thoreau (1817–1862)