|Molecular function||• phosphotyrosine binding
• ubiquitin-protein ligase activity
• signal transducer activity
• epidermal growth factor receptor binding
• calcium ion binding
• zinc ion binding
• SH3 domain binding
|Cellular component||• nucleus
|Biological process||• cell surface receptor signaling pathway
• negative regulation of epidermal growth factor-activated receptor activity
• negative regulation of epidermal growth factor receptor signaling pathway
• protein ubiquitination involved in ubiquitin-dependent protein catabolic process
• negative regulation of MAP kinase activity
|Sources: Amigo / QuickGO|
45.28 – 45.3 Mb
19.78 – 19.8 Mb
Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.
CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999).
Read more about CBLC: Interactions
Other articles related to "cblc":
... CBLC has been shown to interact with FYN and Epidermal growth factor receptor. ...