Autoimmune Disease

Autoimmune Disease

Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response. (For a detailed explanation of pathogenesis see Autoimmunity.)

Read more about Autoimmune Disease:  Criteria, Classification, Development of Therapies

Other articles related to "autoimmune diseases, disease, autoimmune disease, autoimmune, diseases":

Pathogenesis of Autoimmunity
... to be operative in the pathogenesis of autoimmune diseases, against a backdrop of genetic predisposition and environmental modulation ... In coeliac disease it seems likely that B cells recognising tissue transglutamine are helped by T cells recognising gliadin ... Aberrant B cell receptor-mediated feedback - A feature of human autoimmune disease is that it is largely restricted to a small group of antigens ...
Protective Autoimmunity - Regulation
... The outcome of autoimmune activity is determined by several factors, namely the intensity, the location, and the duration of the autoimmune response ... For an autoimmune response to be beneficial, its intensity, duration and site of activity must be tightly regulated ... Although autoimmune T cells exist in all healthy individuals, a relatively small portion of the population develops autoimmune diseases ...
Autoimmune Disease - Development of Therapies
... In both autoimmune and inflammatory diseases the condition arises through aberrant reactions of the human adaptive or innate immune systems ... In inflammatory diseases, it is the overreaction of the immune system, and its subsequent downstream signaling (TNF, IFN, etc.), which causes problems ... A substantial minority of the population suffers from these diseases, which are often chronic, debilitating, and life-threatening ...
Frank Macfarlane Burnet - Walter and Eliza Hall Institute - Immunology
... worked on immunological problems Burnet was involved in work relating to autoimmune diseases and the graft-versus-host reaction, and increasingly in theoretical studies of ... all of the key features of the immune system as we understand it today, including autoimmune disease, immune tolerance and somatic hypermutation as a ... project he worked on at the Institute was a study with assistant Margaret Holmes of autoimmune disease in the New Zealand black mouse model this mouse ...
Causes Of Autism - Postnatal Environment - Autoimmune Disease
... causes for example, viral infection has been hypothesized to cause autism via an autoimmune mechanism ... for example, by infection or autoimmunity, or whether they are secondary to the disease processes ... As autoantibodies are found in diseases other than ASD, and are not always present in ASD, the relationship between immune disturbances and autism remains ...

Famous quotes containing the word disease:

    It is the disease of not listening, the malady of not marking,
    that I am troubled withal.
    William Shakespeare (1564–1616)