DestinationsFurther information: American Airlines destinations
American Airlines serves four continents, trailing Delta Air Lines and United Airlines, which both serve six. Hubs at Dallas/Fort Worth and Miami serve as gateways to the Americas, while American's Chicago hub has become the airline's primary gateway to Europe and Asia. New York Kennedy (JFK) is a primary gateway for both the Americas and Europe, while the Los Angeles hub (LAX) is the primary gateway to Asia. Lambert-St. Louis International Airport served as a regional hub for several years. However, the airline's 2009 restructuring led to the airport being removed as a focus city on April 5, 2010. American serves the third-largest number of international destinations, after United Airlines and Delta Air Lines.
|1||Dallas/Fort Worth, Texas||764|
|4||Los Angeles, California||159|
|5||New York-LaGuardia, New York||102|
|6||New York-JFK, New York||86|
American is the only U.S. airline with scheduled flights to Bolivia and Uruguay and plans to introduce flights to Asuncion, Paraguay's capital city in November 2012.
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