What is dopamine?

  • (noun): A monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension.
    Synonyms: Dopastat, Intropin


Dopamine (abbreviated as DA), a simple organic chemical in the catecholamine family, is a monoamine neurotransmitter which plays a number of important physiological roles in the bodies of animals. In addition to being a catecholamine and a monoamine, dopamine may be classified as a substituted phenethylamine. Its name derives from its chemical structure, which consists of an amine group (NH2) linked to a catechol structure, called dihydroxyphenethylamine, the decarboxylated form of dihydroxyphenylalanine (acronym DOPA). In the brain, dopamine functions as a neurotransmitter—a chemical released by nerve cells to send signals to other nerve cells. The human brain uses five known types of dopamine receptors, labeled D1, D2, D3, D4, and D5. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area.

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Some articles on dopamine:

Biology Of Depression - Abnormalities By Brain Region - Ventral Tegmental Area (VTA)
... It sends projections to the nucleus accumbens that use the neurotransmitter dopamine ... Addictive drugs universally increase the effects of dopamine in this system, whereas drugs that oppose dopamine produce anhedonia of the sort seen in ... Dopamine-enhancers such as cocaine often relieve the lack-of-pleasure in depression, but the effects only last as long as a drug is present in the body that is, they temporarily alleviate one of ...
Dopamine Dysregulation Syndrome
... Dopamine dysregulation syndrome (DDS), sometimes known as hedonistic homeostatic dysregulation in Parkinson's disease, is a dysfunction of the reward ...
Mephedrone - Pharmacology
... cathinones are determined by the differences in how they bind to noradrenalin, dopamine and serotonin transporters ... Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured using HPLC ... Reward and drug seeking are linked to increases in dopamine concentrations in the nucleus accumbens, and drug half-life plays a role in drug seeking, as well ...
Antiparkinson - Examples
... oxidase B inhibitors (To prevent the metabolism of dopamine by MAOB and hence increase its brain levels) Selegiline Rasagiline COMT inhibitors (Preventing the ...
Dopamine - In Plants - Anti-herbivore
... Dopamine is released by the marine alga Ulvaria obscura as an anti-herbivore defense mechanism ...