Tusker can mean:
- an elephant bearing tusks
- an adult male wild boar, particularly the American razorback population
- Tusker (beer), a Kenyan beer bottled by East African Breweries
- The East Africa rugby union team who tour under the nickname The Tuskers
- Tusker FC, a Kenyan football club owned by the East African Breweries
- Florida Tuskers, a franchise in the United Football League
- Kochi Tuskers Kerala, a franchise in the Indian Premier League
- A historic US Army unit, the 4th Battalion, 64th Armored Regiment -- Tuskers
- A range of fork lift solid tyres manufactured by STARCO Group