Systemic Scleroderma

Systemic sclerosis or systemic scleroderma is a systemic autoimmune disease or systemic connective tissue disease that is a subtype of scleroderma. It is characterized by deposition of collagen in the skin and, less commonly, in the kidneys, heart, lungs & stomach. Female to male ratio is 4:1. The peak age of onset is between 30-50 years.

Read more about Systemic Scleroderma:  Signs and Symptoms, Diagnosis, Causes, Pathophysiology, Therapy, Epidemiology, Advocacy

Other articles related to "systemic, scleroderma, systemic scleroderma":

Lidia Rudnicka - Biography - Scleroderma Research
... to the role of Natural Killer Cells and adhesion molecules in systemic sclerosis (scleroderma) and showed that activated peripheral blood mononuclear cells of scleroderma patients ... She is the author of the hypothesis linking etiology of systemic sclerosis to a mutation in the topoisomerase I gene and abnormal topoisomerase I expression ... anti-topoisomerse I antibodies in sera of patients with scleroderma represents a protective reaction to these abnormalities ...
Systemic Scleroderma - Advocacy
... The Juvenile Scleroderma Network is an organization dedicated to provide emotional support and educational information to parents and their children living with juvenile ... In the US, the Scleroderma Research Foundation is dedicated to raise awareness of the disease and assist those who are affected ... The Scleroderma Research Foundation sponsors research into the condition ...
CREST Syndrome
... The limited cutaneous form of systemic scleroderma (lcSSc) is often referred to as CREST syndrome ... Esophageal dysmotility Sclerodactyly Telangiectasia It is a form of systemic scleroderma associated with antibodies against centromeres and usually spares the kidneys ... CREST syndrome is a collection of symptoms seen in limited cutaneous systemic scleroderma and is a systemic inflammatory autoimmune connective tissue ...