Pfizer, Inc. (/ˈfaɪzər/) (NYSE: PFE) is an American multinational pharmaceutical corporation headquartered in New York City, and with its research headquarters in Groton, Connecticut, United States. It is the world's largest pharmaceutical company by revenues.

Pfizer develops and produces medicines and vaccines for a wide range of conditions including in the areas of immunology and inflammation, oncology, cardiovascular and metabolic diseases, neuroscience and pain. Pfizer's products include Lipitor (atorvastatin, used to lower blood cholesterol); the neuropathic pain/fibromyalgia drug Lyrica (pregabalin); the oral antifungal medication Diflucan (fluconazole), the antibiotic Zithromax (azithromycin), Viagra (sildenafil, for erectile dysfunction), and the anti-inflammatory Celebrex (celecoxib) (also known as Celebra in some countries).

Pfizer was founded by cousins Charles Pfizer and Charles Erhart in New York City in 1849 as a manufacturer of fine chemicals. Pfizer's discovery of Terramycin (oxytetracycline) in 1950 put it on a path towards becoming a research-based pharmaceutical company. Pfizer has made numerous acquisitions, including of Warner–Lambert in 2000, Pharmacia in 2003 and Wyeth in 2009, the latter acquired for US$68 billion. Pfizer is listed on the New York Stock Exchange and its shares have been a component of the Dow Jones Industrial Average since April 8, 2004.

In September 2009, Pfizer pleaded guilty to the illegal marketing of the arthritis drug Bextra for uses unapproved by the FDA, and agreed to a $2.3 billion settlement, the largest health care fraud settlement at that time. Pfizer also paid the U.S. government $1.3 billion in criminal fines related to the "off-label" marketing of Bextra, the largest penalty ever rendered for any crime. Called a repeat offender, this was Pfizer's fourth such settlement with the U.S. Department of Justice in the previous ten years.

Read more about PfizerOperations, Litigation, Environmental Record, Political Lobbying, Employment and Diversity, AIDS Involvement

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Pfizer - AIDS Involvement
... Pfizer has been involved in controversies over the medicine Diflucan (generic name fluconazole) ... by Thai public health groups led to the elimination of the Pfizer monopoly on selling fluconazole in Thailand, and the price of the antifungal drug decreased from ... Faced with pressure for compulsory licenses to the Pfizer patent on this drug, Pfizer later established a program for limited access to the medicine in Africa ...
Selectra - Pfizer Advertisements
... form of sertraline, Zoloft, was advertised to consumers by Pfizer using the following wording "While the cause is unknown, depression may be related to an imbalance of ... is no scientific support for the "serotonin imbalance" theory of depression, and criticized Pfizer and manufacturers of other SSRIs for using it ...
SUGEN - Shutdown and Legacy
... The Pfizer-Pharmacia merger lead to major cuts in research activities, including the shut down of Sugen over the course of 2003, with the loss of ... Pfizer continued the phase 3 trials and development of SU11248, now known as Sutent (sunitinib), leading to Food and Drug Administration approval in January 2006 for treatment of RCC ... Other programs also transferred to Pfizer, including a follow-on compound to SU11248, known as SU14813, and programs on Met and PAK kinases ...
Abdullahi V. Pfizer, Inc.
... litigation relates to a 1996 incident when the pharmaceutical company Pfizer conducted tests of trovafloxacin (a quinolone antibiotic) in Nigeria on 100 children, five of whom died ... Pfizer also deliberately reduced the dosage for 100 children with the standard anti-meningitis drug ceftriaxone (a cephalosporin antibiotic) ... The survivors of the trovafloxacin test attempted to bring a number of legal actions against Pfizer in the United States ...
... selective estrogen receptor modulator (SERM), under development by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals ... Pfizer are seeking approval for bazedoxifene in the prevention and treatment of postmenopausal osteoporosis ... When approved, bazedoxifene is to be sold by Pfizer under the tradename Viviant in the US and Conbriza in the EU ...