Mast Cell Leukemia

Mast cell leukemia is an extremely aggressive subtype of acute myeloid leukemia that usually occurs de novo but can, rarely, evolve from transformation of chronic myeloid leukemia into the more aggressive acute myeloid leukemia. In a small proportion of cases, acute mast cell leukemia may evolve from a more progressive form of systemic mastocytosis. The diagnosis of acute mast cell leukemia by the WHO criteria includes the requirement for a prevalence of 20% neoplastic mast cells in marrow and 10% in blood. If the mast cells represent less than 10% of blood cells, the tumor is called "aleukemic" mast cell leukemia.

Read more about Mast Cell LeukemiaClinical Course, Therapy, Prognosis

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Famous quotes containing the words mast and/or cell:

    Alas for America as I must so often say, the ungirt, the diffuse, the profuse, procumbent, one wide ground juniper, out of which no cedar, no oak will rear up a mast to the clouds! It all runs to leaves, to suckers, to tendrils, to miscellany. The air is loaded with poppy, with imbecility, with dispersion, & sloth.
    Ralph Waldo Emerson (1803–1882)

    each in the cell of himself is almost convinced of his freedom,
    —W.H. (Wystan Hugh)