Infective Endocarditis

Infective endocarditis is a form of endocarditis, or inflammation, of the inner tissue of the heart, such as its valves, caused by infectious agents. The agents are usually bacterial, but other organisms can also be responsible.

The valves of the heart do not receive any dedicated blood supply. As a result, defensive immune mechanisms (such as white blood cells) cannot directly reach the valves via the bloodstream. If an organism (such as bacteria) attaches to a valve surface and forms a vegetation, the host immune response is blunted. The lack of blood supply to the valves also has implications for treatment, since drugs also have difficulty reaching the infected valve.

Normally, blood flows smoothly through these valves. If they have been damaged - from rheumatic fever, for example - the risk of bacterial attachment is increased.

Read more about Infective Endocarditis:  Signs and Symptoms, Cause, Pathogenesis, Diagnosis, Micro-organisms Responsible, Treatment

Other articles related to "infective endocarditis, endocarditis":

Infective Endocarditis
... valvular disease (including mitral valve prolapse, reinfection in the form of valvular endocarditis, and valve rupture) from undertreated rheumatic fever continues to be a problem ... In an Indian hospital between 2004 and 2005, 4 of 24 endocarditis patients failed to demonstrate classic vegetatations ...
Infective Endocarditis - Treatment
... In acute endocarditis, due to the fulminant inflammation empirical antibiotic therapy is started immediately after the blood has been drawn for culture ... be noted that the routine use of gentamicin to treat endocarditis has fallen out of favor due to the lack of evidence to support its use (except in infections caused by Enterococcus and nutritionally ... In subacute endocarditis, where patient's hemodynamic status is usually stable, antibiotic treatment can be delayed till the causative microorganism can be identified ...
Non-infective Endocarditis
... Nonbacterial thrombic endocarditis (NBTE) or marantic endocarditis is most commonly found on previously undamaged valves ... As opposed to infective endocarditis, the vegetations in NBTE are small, sterile, and tend to aggregate along the edges of the valve or the cusps ... Also unlike infective endocarditis, NBTE does not cause an inflammation response from the body ...
Mitral Valve Prolapse - Treatment - Prevention of Infective Endocarditis
... with MVP are at higher risk of bacterial infection of the heart, called infective endocarditis ... approximately three- to eightfold the risk of infective endocarditis in the general population ... with the highest risk of adverse outcome from infective endocarditis." Many organisms responsible for endocarditis are slow-growing and may not be easily identified on routine ...