Hyperthermia is elevated body temperature due to failed thermoregulation that occurs when a body produces or absorbs more heat than it dissipates. Extreme temperature elevation then becomes a medical emergency requiring immediate treatment to prevent disability or death.

Common causes include heat stroke and adverse reactions to drugs. The former is an acute hyperthermia caused by exposure to excessive heat, or combination of heat and humidity, that overwhelms the heat-regulating mechanisms of the body causing uncontrollable elevation of body temperature. The latter is a relatively rare side effect of many drugs, particularly those that affect the central nervous system. Malignant hyperthermia is a rare complication of some types of general anesthesia.

Hyperthermia can be deliberately induced using drugs or medical devices and may be used to treat some kinds of cancer and other conditions, most commonly in conjunction with radiotherapy.

Hyperthermia differs from fever in that the body's temperature set point remains unchanged. The opposite is hypothermia, which occurs when an organism's temperature drops below that required to maintain normal metabolism.

Read more about HyperthermiaClassification, Signs and Symptoms, Pathophysiology, Diagnosis, Prevention, Treatment, Epidemiology

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Hyperthermia - Epidemiology
... The frequency of environmental hyperthermia can vary significantly from year to year depending on factors such as heat waves ...
Hyperthermia Therapy - Future Directions
... Hyperthermia may be combined with gene therapy, particularly using the heat shock protein 70 promoter ... Two major technological challenges make hyperthermia therapy complicated the ability to achieve a uniform temperature in a tumor, and the ability to precisely monitor the ... of middle and lower rectum, regional hyperthermia added to chemoradiotherapy achieved good results in terms of rate of sphincter sparing surgery ...
Suxamethonium - Adverse Effects - Malignant Hyperthermia
... Malignant hyperthermia from suxamethonium administration can result in a drastic and uncontrolled increase in skeletal muscle oxidative metabolism ... Susceptibility to malignant hyperthermia (MH) is often inherited as an autosomal dominant disorder, for which there are at least six genetic loci of interest, the most ...
Hyperthermia Therapy
... Hyperthermia therapy is a type of medical treatment in which body tissue is exposed to slightly higher temperatures to damage and kill cancer cells or to make cancer cells more ... Local hyperthermia for certain small tumors is generally accepted, similar to surgically removing a tumor ... Whole-body hyperthermia is generally considered to be a promising experimental cancer treatment ...
Hyperthermia Therapy - History
... practitioners in ancient India used regional and whole-body hyperthermia as treatments ... the same period Westermark used localized hyperthermia to produce tumor regression in patients ... Properly controlled clinical trials on deliberately induced hyperthermia began in the 1970s ...