DNA Synthesis

DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules. In nature, such molecules are created by all living cells through the process of DNA replication, with replication initiator proteins splitting the existing DNA of the cell and making a copy of each split segment, with the copied segments then being joined together into a new DNA molecule. Various means also exist to artificially stimulate the replication of naturally occurring DNA, or to create artificial gene sequences. A polymerase chain reaction is a form of enzymatic DNA synthesis, using cycles of repeated heating and cooling of the reaction for DNA melting and enzymatic replication of the DNA. Artificial gene synthesis is the process of synthesizing a gene in vitro without the need for initial template DNA samples. The main method is currently by oligonucleotide synthesis (also used for other applications) from digital genetic sequences and subsequent annealing of the resultant fragments.

Other articles related to "dna synthesis, synthesis, dna":

Megaloblastic Anemia
... an anemia (of macrocytic classification) that results from inhibition of DNA synthesis in red blood cell production ... When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage ... The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically a deficiency of vitamin B and/or folic acid ...
Pralatrexate - Mechanism
... with structural similarity to naturally occurring molecules involved in DNA synthesis ... metabolites allowing the compound to stop or slow critical enzymes involved in DNA synthesis which then triggers cell death ... Because of their primary effect on DNA synthesis, the antimetabolites are most effective against actively dividing cells and are largely cell-cycle ...
Folic Acid - Biological Roles - DNA and Cell Division
... Folate is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis, and for preventing changes to DNA, and, thus, for preventing cancer ... methylation reactions and nucleic acid synthesis (the most notable one being thymine, but also purine bases) ... Thus, folate deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of their greater frequency of cell division ...
DNA Polymerase II
... DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA polymerase most likely involved in DNA repair ... DNA Pol II can synthesize DNA new base pairs at an average rate of between 40 and 50 nucleotides/second ... Synthesis of Pol II is induced during the stationary phase of cell growth ...

Famous quotes containing the words synthesis and/or dna:

    The new shopping malls make possible the synthesis of all consumer activities, not least of which are shopping, flirting with objects, idle wandering, and all the permutations of these.
    Jean Baudrillard (b. 1929)

    Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.
    William Gibson (b. 1948)