DNA Polymerase Beta
|Molecular function||• damaged DNA binding
• DNA-directed DNA polymerase activity
• protein binding
• microtubule binding
• lyase activity
• enzyme binding
• metal ion binding
|Cellular component||• nucleus
• spindle microtubule
|Biological process||• DNA-dependent DNA replication
• DNA repair
• base-excision repair
• pyrimidine dimer repair
• nucleotide-excision repair, DNA gap filling
• response to DNA damage stimulus
• cell death
• response to ethanol
|Sources: Amigo / QuickGO|
42.2 – 42.23 Mb
22.63 – 22.65 Mb
|Stem loopII regulatory element in POLB|
|Predicted secondary structure of the stem loopII (M2) regulatory element in POLB|
|Locus||Chr. 8 p11.2|
Polymerase (DNA directed), beta, also known as POLB, is an enzyme that, in humans, is encoded by the POLB gene.
Other articles related to "polymerase, dna polymerase, dna, polymerases, dna polymerase beta":
... A polymerase is an enzyme whose central biological function is the synthesis of polymers of nucleic acids ... DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, generally by copying a DNA or RNA template strand using base-pairing ... generation of other biopolymers are not also referred to as polymerases ...
... acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell ... Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription ...
... DNA polymerase beta has been shown to interact with PNKP and XRCC1. ...
... The linear vector DNA already has the topoisomerase enzyme covalently attached to both of its strands' free 3' ends ... types of vectors are used for cloning fragments amplified by either Taq or Pfu polymerase as Taq polymerase (unlike Pfu) leaves an extra "A" nucleotide at the 3'end during ... (A) and thymine (T) (complementary basepairs) on different DNA fragments to hybridize and, in the presence of ligase or topoisomerase, become ligated together ...
... The T7 DNA polymerase of the T7 bacteriophage is a DNA-dependent DNA polymerase responsible for the fast rate of T7 phage DNA replication in vivo ... The polymerase consists of a 11 complex of the viral T7 gene 5 protein (80kDA) and the E ... This polymerase is unique due to its considerable processivity, or ability to stay on DNA for a greater than average number of base pairs ...
Famous quotes containing the word dna:
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