DNA Polymerase Beta

DNA Polymerase Beta

Identifiers Symbols POLB; MGC125976 External IDs OMIM: 174760 MGI: 97740 HomoloGene: 2013 ChEMBL: 2392 GeneCards: POLB Gene EC number

Gene Ontology
Molecular function damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
microtubule binding
lyase activity
enzyme binding
metal ion binding
Cellular component nucleus
spindle microtubule
Biological process DNA-dependent DNA replication
DNA repair
base-excision repair
pyrimidine dimer repair
nucleotide-excision repair, DNA gap filling
response to DNA damage stimulus
cell death
response to ethanol
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5423 18970 Ensembl ENSG00000070501 ENSMUSG00000031536 UniProt P06746 Q8K409 RefSeq (mRNA) NM_002690 NM_011130 RefSeq (protein) NP_002681 NP_035260 Location (UCSC) Chr 8:
42.2 – 42.23 Mb Chr 8:
22.63 – 22.65 Mb PubMed search
Stem loopII regulatory element in POLB
Predicted secondary structure of the stem loopII (M2) regulatory element in POLB
Symbol POLB
Rfam RF01455
Entrez 5423
OMIM 174760
RefSeq NM_002690
Other data
RNA type Cis-reg
Domain(s) Mammalia
Locus Chr. 8 p11.2

Polymerase (DNA directed), beta, also known as POLB, is an enzyme that, in humans, is encoded by the POLB gene.

Read more about DNA Polymerase Beta:  Function, Regulation of Expression, Interactions

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