Identifiers Symbols CASK; CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8 External IDs OMIM: 300172 MGI: 1309489 HomoloGene: 2736 GeneCards: CASK Gene EC number

Gene Ontology
Molecular function guanylate kinase activity
protein serine/threonine kinase activity
protein binding
calmodulin binding
ATP binding
neurexin family protein binding
Cellular component basement membrane
nuclear lamina
plasma membrane
cell-cell junction
actin cytoskeleton
basolateral plasma membrane
nuclear matrix
presynaptic membrane
cilium membrane
Biological process negative regulation of cell-matrix adhesion
cell adhesion
negative regulation of keratinocyte proliferation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of wound healing
calcium ion import
positive regulation of calcium ion import
negative regulation of cellular response to growth factor stimulus
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 8573 12361 Ensembl ENSG00000147044 ENSMUSG00000031012 UniProt O14936 O70589 RefSeq (mRNA) NM_001126054 NM_009806 RefSeq (protein) NP_001119526 NP_033936 Location (UCSC) Chr X:
41.37 – 41.78 Mb Chr X:
13.52 – 13.85 Mb PubMed search

Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2.

Read more about CASK:  Gene, Function, Clinical Importance, Interactions

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CASK - Interactions
... CASK has been shown to interact with KCNJ4, APBA1, ATP2B4, CINAP and TBR1, DLG1, DLG4, F11 receptor, ID1, KCNJ12 LIN7A, Nephrin, Parkin (ligase), RPH3A ...

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