What is omeprazole?

  • (noun): Antacid (trade name Prilosec) that suppresses acid secretion in the stomach.
    Synonyms: Prilosec


Omeprazole (INN) ( /oʊˈmɛprəzoʊl/) (Prilosec and generics) is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), laryngopharyngeal reflux (LPR) and Zollinger–Ellison syndrome. Omeprazole is one of the most widely prescribed drugs internationally and is available over the counter in some countries.

Read more about Omeprazole.

Some articles on omeprazole:

Lensor - Pharmacokinetics - Measurement in Body Fluids
... Omeprazole may be quantitated in plasma or serum to monitor therapy or to confirm a diagnosis of poisoning in hospitalized patients ... Plasma omeprazole concentrations are usually in a range of 0.2–1.2 mg/L in persons receiving the drug therapeutically via the oral route and 1–6 mg/L in victims of acute overdosage ... chromatographic methods are available to distinguish esomeprazole from racemic omeprazole ...
Lensor - Dosage Forms
... Omeprazole is available as tablets and capsules (containing omeprazole or omeprazole magnesium) in strengths of 10 mg, 20 mg, 40 mg, and in some markets 80 mg ... Most oral omeprazole preparations are enteric-coated, due to the rapid degradation of the drug in the acidic conditions of the stomach ... a white to off-white lyophilised powder consisting of omeprazole sodium 42.6 mg equivalent to 40 mg of omeprazole ...
Omeprazole - Dosage Forms - Immediate Release Formulation
... In June 2004 the FDA approved an immediate release preparation of omeprazole and sodium bicarbonate that does not require an enteric coating ... sodium bicarbonate as a buffer to protect omeprazole from gastric acid degradation ...
Lensor - Adverse Effects - Interactions
... Omeprazole is a competitive inhibitor of the enzymes CYP2C19 and CYP2C9, and may therefore interact with drugs that depend on them for metabolism, such as diazepam, escitalopram, and ... Omeprazole is also a competitive inhibitor of p-glycoprotein, as are other PPIs ... pH for absorption may interact with omeprazole drugs that depend on an acidic environment (such as ketoconazole or atazanavir) will be poorly absorbed, whereas acid-labile antibiotics (such as erythromycin ...
Lensor - History
... Omeprazole was first marketed in the U.S ... The new name has led to confusion between omeprazole (Prilosec) and fluoxetine (Prozac), an antidepressant ... AstraZeneca markets omeprazole as Losec, Antra, Gastroloc, Mopral, Omepral, and Prilosec ...