What is ncam?

Some articles on ncam:

Polysialic Acid
... is an unusual posttranslational modification that occurs on neural cell adhesion molecules (NCAM) ... In the synapse, polysialation of NCAM prevents its ability to bind to NCAM's on the adjacent membrane ...
Nerve Guidance Conduit - Scaffold Material - Biological Polymers - Polysialic Acid (PSA)
... modification of the neural cell adhesion molecule (NCAM) ... Recent studies have demonstrated that polysialylated NCAM (polySia-NCAM) promotes regeneration in the motor system ...
Neural Cell Adhesion Molecule - Anti-NCAM Therapy
... NCAM has been used as a target molecule for experimental antibody-based immunotherapy ... of metastases was demonstrated after giving injections of NCAM-binding 123J-UJ13a or 131J-UJ13a radioimmunoconjugates to children with neuroblastoma ... Patients with small cell lung cancer were treated with the anti-NCAM immunotoxine huN901-DM1 in two different clinical studies, revealing acceptable toxicity and signs of clinical response ...
Rostral Migratory Stream - Migration Mechanics - Glial Framework
... a polysialylated (PSA) embryonic form of the neural cell adhesion molecule (NCAM) called PSA-NCAM, as well as β-tubulin, a protein often found in postmitotic neuroblasts, proving the cells of RMS are ... With the removal of NCAM, the neuroblasts scatter, proving the importance of NCAM in chain formation ...
Neural Cell Adhesion Molecule - Forms, Domains and Homophilic Binding
... NCAM is a glycoprotein of Immunoglobulin(Ig)superfamily ... At least 27 alternatively spliced NCAM mRNAs are produced, giving a wide diversity of NCAM isoforms ... The three main isoforms of NCAM vary only in their cytoplasmic domain NCAM-120kDa (GPI anchored) NCAM-140kDa (short cytoplasmic domain) NCAM-180kDa (long cytoplasmic domain ...