What are hemostasis?

Hemostasis

Hemostasis or haemostasis (from the Ancient Greek: αἱμόστασις haimóstasis "styptic (drug)") is a process which causes bleeding to stop, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage). It is the first stage of wound healing. Most of the time this includes blood changing from a liquid to a solid state. All situations that may lead to hemostasis are portrayed by the Virchow's triad. Intact blood vessels are central to moderating blood's tendency to clot. The endothelial cells of intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin and prevent platelet aggregation with nitric oxide and prostacyclin. When endothelial injury occurs, the endothelial cells stop secretion of coagulation and aggregation inhibitors and instead secrete von Willebrand factor which initiate the maintenance of hemostasis after injury. Hemostasis has three major steps: 1) vasoconstriction, 2) temporary blockage of a break by a platelet plug, and 3) blood coagulation, or formation of a clot that seals the hole until tissues are repaired.

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Some articles on hemostasis:

Bone Hemostasis
... Bone hemostasis is the process of controlling the bleeding from bone ... blocking the holes and causing immediate hemostasis ...
Coagulation - Role in Disease - Disease and Clinical Significance of Thrombosis
... This binding helps mediate the activation of platelets and formation of primary hemostasis ... for vWF, can be defective and lead to lack of primary clot formation (primary hemostasis) and increased bleeding tendency ... platelets, which inhibits primary hemostasis ...
Skin Biopsy - Types - Shave Biopsy
... Hemostasis is obtained using light electrocautery, Monsel's solution, or aluminum chloride ... Hemostasis for the shave technique can be difficult if one relied on electrocautery alone ... Pressure dressing or chemical astringent can help in hemostasis in patients taking anticoagulants ...
Hemostasis - Hemostatic Research
... There is currently a lot of research being conducted on hemostasis ... current research is based on genetic factors of hemostasis and how it can be altered to reduce the cause of genetic disorders that alter the natural process hemostasis ... This disease negatively hinders the natural process of Hemostasis causing excessive bleeding to be a concern in patients with this disease ...
Human Homeostasis - Blood Composition - Hemostasis
... Hemostasis is the process whereby bleeding is halted ... Unlike the majority of control mechanisms in human body, the hemostasis utilizes positive feedback, for the more the clot grows, the more clotting occurs, until the blood stops ...