What are cholestasis?

  • (noun): A condition in which little or no bile is secreted or the flow of bile into the digestive tract is obstructed.
    Synonyms: acholia


In medicine, cholestasis is a condition where bile cannot flow from the liver to the duodenum. The two basic distinctions are an obstructive type of cholestasis where there is a mechanical blockage in the duct system such as can occur from a gallstone or malignancy, and metabolic types of cholestasis which are disturbances in bile formation that can occur because of genetic defects or acquired as a side effect of many medications.

Read more about Cholestasis.

Some articles on cholestasis:

Cholestasis - Symptoms
... Pruritus is the primary symptom of cholestasis and is thought to be due to interactions of serum bile acids with opioidergic nerves ... opioid agonist/antagonist Naltrexone is used to treat pruritus due to cholestasis ... Jaundice is an uncommon occurrence in intrahepatic cholestasis, but is common in obstructive cholestasis ...
Intrahepatic Cholestasis Of Pregnancy
... Intrahepatic cholestasis of pregnancy, termed obstetric cholestasis in the United Kingdom, (also known as "cholestasis of pregnancy," "jaundice of pregnancy," and "pru ...
List Of Diseases (C) - Ch - Cho - Choa–Chol
... cyst, hand malformation Cholelithiasis Cholemia, familial Cholera Cholestasis pigmentary retinopathy cleft palate Cholestasis, progressive familial intrahepatic 1 Cholestasis, progressive ...
Lipoprotein-X - Pathogenesis
... The pathogenesis of lipoprotein-X in cholestasis is not totally resolved ... causes the formation of lipoprotein-X in cholestasis as a result of a physicochemical, nonmetabolic process ... deficiency are identical to those in cholestasis regarding ultrastructure and biochemical composition ...
Progressive Familial Intrahepatic Cholestasis
... Progressive familial intrahepatic cholestasis (PFIC) refers to a group of familial cholestatic conditions caused by defects in biliary epithelial transporters ... presentation usually occurs first in childhood with progressive cholestasis ...