What are amelogenesis?

  • (noun): The developmental process of forming tooth enamel.


Amelogenesis is the formation of enamel on teeth and occurs during the crown stage of tooth development after dentinogenesis, which is the formation of dentine. Although dentine must be present for enamel to be formed, it is also true that ameloblasts must be present in order for dentinogenesis to continue. A message is sent from the newly differentiated odontoblasts to the inner enamel epithelium (IEE), causing the epithelial cells to further differentiate into active secretory ameloblasts. Dentinogenesis is in turn dependent on signals from the differentiating IEE in order for the process to continue. This prerequisite is an example of the biological concept known as reciprocal induction, in this instance between mesenchymal and epithelial cells.

Read more about Amelogenesis.

Some articles on amelogenesis:

Amelogenesis Imperfecta
... Amelogenesis imperfecta presents with abnormal formation of the enamel or external layer of teeth ... Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel ameloblastin, enamelin, tuftelin and amelogenin ... People afflicted with amelogenesis imperfecta have teeth with abnormal color yellow, brown or grey ...
List Of Diseases (A) - Am - Ama–Amy
... iris coloboma Amelia facial dysmorphism Amelia X linked Amelogenesis Amelogenesis Imperfecta hypomaturation type Amelogenesis imperfecta local hypoplastic form Amelogenesis imperfecta nephrocalcinosis Amelogenesis ...
Amelogenesis - Stages - Maturation Stage
... The undermineralised, immature enamel containing long, thin prisms of hydroxyapatite, matures ... As the prisms in the enamel grow in thickness (not length), proteins (amelogenins and most non-amelogenins) are removed from the matrix to give more space for hydroxyapatite deposition - mature crystals are hexagonal and 25x75nm and can run the whole length of the enamel (up to 2.5mm) ...
Amelogenesis Imperfecta - Genetics
... MMP20, and KLK-4 genes have been found to cause amelogenesis imperfecta (non-syndromic form) ... Researchers are looking for mutations in other genes that may also cause amelogenesis imperfecta ... AI2A3 613211 WDR72 15q21.3 AI3 130900 FAM83H 8q24.3 AIH1 301200 AMELX Xp22.3-p22.1 Amelogenesis imperfecta can have different inheritance patterns depending on the gene that is altered ...