Transglutaminase

A transglutaminase is an enzyme that catalyzes the formation of a covalent bond between a free amine group (e.g., protein- or peptide-bound lysine) and the gamma-carboxamide group of protein- or peptide-bound glutamine. Such an enzyme is classified as EC 2.3.2.13. Bonds formed by transglutaminase exhibit high resistance to proteolytic degradation (proteolysis).

Transglutaminases were first described in 1959. The exact biochemical activity of transglutaminases was discovered in blood coagulation protein factor XIII in 1968.

Read more about TransglutaminasePhysiological Transglutaminases, Mechanism of Action, Role in Disease, Industrial and Culinary Applications, Molecular Gastronomy

Other articles related to "transglutaminase, transglutaminases":

Anti-transglutaminase Antibodies
... Anti-transglutaminase antibodies (ATA) are autoantibodies against the transglutaminase protein ... ATA can be classified according to 2 different schemes transglutaminase isoform and immunoglobulin reactivity subclass (IgA, IgG) toward transglutaminases ...
Protein-glutamine Gamma-glutamyltransferase - Nomenclature
... stabilizing factor, fibrinoligase, glutaminylpeptide gamma-glutamyltransferase, polyamine transglutaminase, R-glutaminyl-peptideamine gamma-glutamyl transferase ...
Transglutaminase - Molecular Gastronomy
... Transglutaminase is also used in molecular gastronomy to meld new textures with existing tastes ... Besides these mainstream uses, transglutaminase has been used to create some unusual foods ... British chef Heston Blumenthal is credited with the introduction of transglutaminase into modern cooking ...
Anti-transglutaminase Antibodies - Mechanism of Autoimmunity
... The antibodies to tissue transglutaminase follow a complex pathway of generation ... Gliadin is a favored dietary substrate for transglutaminase because of many enzyme reaction sites on gliadin ... In disease, transglutaminase reacts with gliadin forming a linkage ...
Anti-transglutaminase Antibodies - Transglutaminase Isoform Reactivity - Anti-epidermal Transglutaminase
... Antibodies to epidermal transglutaminase (eGT, also keratinocyte transglutaminase) are the autoantibodies believed to cause dermatitis herpetiformis ...