Serum Free Light Chain Measurement

Serum Free Light Chain Measurement

Measurement of immunoglobulin-free light chains in serum has recently become possible. These tests are used as an aid in the diagnosis and monitoring of multiple myeloma and related disorders. There are two types of immunoglobulin light chain produced in humans, designated by the Greek letters kappa (κ) and lambda (λ). Comparing the ratio of kappa-to-lambda free-light chains in the serum of an individual with that measured in a number of subjects known to be disease-free indicates whether the individual might have a plasma cell tumour such as multiple myeloma or AL amyloidosis.

Read more about Serum Free Light Chain Measurement: Structure, Synthesis, Production, Metabolism, Clinical Use, Guidelines, External Links

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