A sclerotome is part of a somite, a structure in vertebrate embryonic development. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra.

From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch. Other cells move distally to the costal processes of thoracic vertebrae to form the ribs.

Other articles related to "sclerotome, sclerotomes":

Human Vertebral Column - Regions - Development
... dorsally, which gives rise to the muscles and dermis, and the sclerotome ventrally, which will form the spine components ... Sclerotomes become subvidided into an anterior and a posterior compartment ... the fourth week of embryonic development, the sclerotomes shift their position to surround the spinal cord and the notochord ...