Samuel H. Wood - Cloning

Cloning

Wood entered the arena of stem cell research shortly after the first published study of nuclear transfer stem cells (NTSC), also known as human therapeutic cloning, was withdrawn when the principal author's claims were called into question due to falsified data and ethical deviation from scientific research standards. Australian scientist, Andrew French, best known for his work with somatic cell nuclear transfer (SCNT) in the mammalian reproduction process, co-investigated with Wood and French's Australian colleague, Alan Trounson. Based on meticulous mammalian study review, the researchers concluded that the rigorous procedures developed for mammalian reproduction held promise for practical application in human embryonic stem cell (hESC) line production. Furthermore, they specifically proposed hESC research should steer away from attempting to produce viable offspring, focusing efforts on the use of cloned embryos as a viable source for deriving stem cell lines instead.

In 2008, Wood created embryo copies of himself by placing his skin cells in a woman's egg, marking the first time anyone had done so with adult skin cells. The five cloned embryos were later destroyed, In January 2008, Wood and Andrew French, Stemagen's chief scientific officer in California, announced that they had successfully created the first five mature human embryos using DNA from adult skin cells, aiming to provide a less-controversial source of viable embryonic stem cells. Dr. Wood and a colleague donated skin cells and the DNA from those cells was transferred into human eggs. It is not clear if the embryos produced would have been capable of further development, but Dr. Wood stated that if that were possible, using the technology for reproductive cloning would be both unethical and illegal. The five cloned embryos, created in Stemagen Corporation lab in La Jolla, were later destroyed. Ethics concerns were subsequently raised.

Wood and five other researchers published their findings in the online research journal Stem Cells in an article entitled Development of Human cloned Blastocyst Following Somatic Cell Nuclear Transfer (SCNT) with Adult Fibroblasts.

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Other articles related to "cloning":

American Anti-Vivisection Society - Campaigns - Animal Cloning
... recent concern of the organization is that of animal cloning ... Animal cloning has a 1 to 4 percent success rate, meaning that 96 to 99 percent of animals attempting to be cloned die or are never fully created ... With cloning animals for consumer use, this brings into question the potential for human cloning and the government’s ethical standpoint on such an idea ...
Cloning - In Science Fiction
... Cloning has been used in countless science fiction works throughout the years ... Human cloning is usually most popular, mainly due to fact that it brings up controversial questions of identity ... prescient novel Brave New World (1932), human cloning is a major plot device that not only drives the story along but also makes the reader think ...
Swipe (comics) - "Cloning"
... Though not technically swiping, some artists have made a career "cloning" other artists ... Industry veteran Dick Giordano maintained that cloning is not only acceptable, but actually preferable, when an artist fills in for a regular artist on a title ...
Steps in Molecular Cloning - Preparation of DNA To Be Cloned
... For cloning of genomic DNA, the DNA to be cloned is extracted from the organism of interest ... used for amplification of specific DNA or RNA (RT-PCR) sequences prior to molecular cloning ... DNA for cloning experiments may also be obtained from RNA using reverse transcriptase (complementary DNA or cDNA cloning), or in the form of synthetic DNA (artificial gene synthesis) ...

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