|Example 1: risk reduction||Example 2: risk increase|
|Experimental group (E)||Control group (C)||Total||(E)||(C)||Total|
|Events (E)||EE = 15||CE = 100||115||EE = 75||CE = 100||175|
|Non-events (N)||EN = 135||CN = 150||285||EN = 75||CN = 150||225|
|Total subjects (S)||ES = EE + EN = 150||CS = CE + CN = 250||400||ES = 150||CS = 250||400|
|Event rate (ER)||EER = EE / ES = 0.1, or 10%||CER = CE / CS = 0.4, or 40%||EER = 0.5 (50%)||CER = 0.4 (40%)|
|Equation||Variable||Abbr.||Example 1||Example 2|
|CER − EER||< 0: absolute risk reduction||ARR||(−)0.3, or (−)30%||N/A|
|> 0: absolute risk increase||ARI||N/A||0.1, or 10%|
|(CER − EER) / CER||< 0: relative risk reduction||RRR||(−)0.75, or (−)75%||N/A|
|> 0: relative risk increase||RRI||N/A||0.25, or 25%|
|1 / (CER − EER)||< 0: number needed to treat||NNT||(−)3.33||N/A|
|> 0: number needed to harm||NNH||N/A||10|
|EER / CER||relative risk||RR||0.25||1.25|
|(EE / EN) / (CE / CN)||odds ratio||OR||0.167||1.5|
|EER − CER||attributable risk||AR||(−)0.30, or (−)30%||0.1, or 10%|
|(RR − 1) / RR||attributable risk percent||ARP||N/A||20%|
|1 − RR (or 1 − OR)||preventive fraction||PF||0.75, or 75%||N/A|
Read more about this topic: Relative Risk Reduction
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