Raney Nickel - Applications - Applications in Organic Synthesis - Reduction of Functional Groups

Reduction of Functional Groups

See also: Reduction of nitro compounds

It is typically used in the reduction of compounds with multiple bonds, such as alkynes, alkenes, nitriles, dienes, aromatics and carbonyl-containing compounds. Additionally, Raney nickel will reduce heteroatom-heteroatom bonds, such as hydrazines, nitro groups, and nitrosamines. It has also found use in the reductive alkylation of amines and the amination of alcohols.

When reducing a carbon-carbon double bond, Raney nickel will add hydrogen in a syn fashion.

Read more about this topic:  Raney Nickel, Applications, Applications in Organic Synthesis

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