Pthrp

Some articles on pthrp:

Parathyroid Hormone-related Protein - Function - Tooth Eruption
... PTHrP is critical in the intraosseous phase of tooth eruption where it acts as a signalling molecule to stimulate local bone resorption ... Without PTHrP, the bony crypt surrounding the tooth follicle will not resorb, and therefore the tooth will not erupt ... In the context of tooth eruption, PTHrP is secreted by the cells of the Reduced Enamel Epithelium ...
Parathyroid Hormone-related Protein - Function - Humoral Hypercalcemia of Malignancy
... PTHrP is related in function to the "normal" parathyroid hormone ... When a tumor secretes PTHrP, this can lead to hypercalcemia ... PTHrP shares the same N-terminal end as parathyroid hormone and therefore it can bind to the same receptor, the Type I PTH receptor (PTHR1) ...