Orthobunyavirus - Virology

Virology

  • The type species is the Bunyamwera Virus.
  • The virus is spherical, diameter 80 nm to 120 nm, and comprises three single stranded RNA molecules encapsulated in a ribonucleocapsid.
  • The three RNAs are described as S, M and L (for Small, Medium and Large) and are circa 1kb (kilobases), 4.5kb and 6.5kb in length
  • The S RNA encodes the Nucleocapsid protein (N protein) and a non structural protein (NS Protein).
  • The M RNA encodes a polyprotein which is cleaved by host protease into Gn, NSm and Gc proteins.
  • The L RNA encodes the viral RNA dependent RNA Polymerase or L Protein

Read more about this topic:  Orthobunyavirus

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