The natural function of this receptor appears to be in regulation of tissue growth, and it has been shown to be important in embryonic development, wound repair, and certain forms of cancer.
OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported.
Read more about this topic: OGFr
Other articles related to "function":
... differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original function is retrieved ... theorem of calculus, allows one to compute integrals by using an antiderivative of the function to be integrated ...
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance, a vector in R3 ... Just as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the double integral of a positive function of ... The same volume can be obtained via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between the ...
Famous quotes containing the word function:
“Morality and its victim, the motherwhat a terrible picture! Is there indeed anything more terrible, more criminal, than our glorified sacred function of motherhood?”
—Emma Goldman (18691940)
“Think of the tools in a tool-box: there is a hammer, pliers, a saw, a screwdriver, a rule, a glue-pot, nails and screws.The function of words are as diverse as the functions of these objects.”
—Ludwig Wittgenstein (18891951)
“We are thus able to distinguish thinking as the function which is to a large extent linguistic.”
—Benjamin Lee Whorf (18971934)