Neurogenic Inflammation

Neurogenic inflammation is inflammation arising from the local release from afferent neurons of inflammatory mediators such as Substance P and Calcitonin Gene-Related Peptide (CGRP).

This process appears to play an important role in the pathogenesis of numerous diseases including psoriasis, asthma, fibromyalgia, eczema, rosacea, dystonia, multiple chemical sensitivity, and migraine.

In migraine, stimulation of the trigeminal nerve causes neurogenic inflammation via release of neuropeptides including Substance P, nitric oxide, vasoactive intestinal polypeptide, 5-HT, Neurokinin A and CGRP. leading to a "sterile neurogenic inflammation."

Read more about Neurogenic InflammationTreatment, Prevention

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Neurogenic Inflammation - Prevention
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