Monoclonal Antibody Therapy - Targeted Conditions - Autoimmune Diseases

Autoimmune Diseases

Monoclonal antibodies used for autoimmune diseases include infliximab and adalimumab, which are effective in rheumatoid arthritis, Crohn's disease and ulcerative Colitis by their ability to bind to and inhibit TNF-α. Basiliximab and daclizumab inhibit IL-2 on activated T cells and thereby help preventing acute rejection of kidney transplants. Omalizumab inhibits human immunoglobulin E (IgE) and is useful in moderate-to-severe allergic asthma.

Read more about this topic:  Monoclonal Antibody Therapy, Targeted Conditions

Other articles related to "autoimmune diseases, autoimmune disease, diseases, autoimmune, disease":

Exosome Complex - Disease - Autoimmunity
... exosome complex is the target of autoantibodies in patients that suffer from various autoimmune diseases ... from the PM/Scl overlap syndrome, an autoimmune disease in which patients have symptoms from both scleroderma and either polymyositis or dermatomyositis ... In these diseases, antibodies are mainly directed against two of the proteins of the complex, called PM/Scl-100 (the RNase D like protein) and PM/Scl-75 (one of the RNase PH like proteins from the ...
Postural Orthostatic Tachycardia Syndrome - Causes
... An autoimmune process has been suggested as a causal mechanism in many POTS patients, supported by the finding of autoantibodies against ganglionic alpha 3 acetylcholine ... it has been suggested that POTS patients exhibit higher comorbid autoimmune diseases than the general population and frequently report a family history of ... with autonomic neuropathy) infectious or acute diseases, such as HIV, Diphtheria, Chagas Disease, Lyme Disease, and Guillain Barre Syndrome chronic diseases, such as CIDP, Diabetes ...
STIM2 Function
... Moreover, it is involved in tumorigenesis, the development of autoimmune diseases and mechanisms of neuronal damage after transient ischemic conditions ... which presumably are important in early phases of autoimmune diseases ... In fact, STIM2-deficient mice showed mild symptomatology in the early phase of autoimmune diseases ...
CNS Demyelinating Autoimmune Diseases
... CNS demyelinating autoimmune diseases are autoimmune diseases which primarily affect the central nervous system ...

Famous quotes containing the word diseases:

    But what is quackery? It is commonly an attempt to cure the diseases of a man by addressing his body alone. There is need of a physician who shall minister to both soul and body at once, that is, to man. Now he falls between two stools.
    Henry David Thoreau (1817–1862)