Minisatellites

Some articles on minisatellite, minisatellites:

Minisatellite
... A minisatellite (also referred as VNTR) is a section of DNA that consists of a short series of bases 10–60 bp ... Some minisatellites contain a central (or "core") sequence of letters “GGGCAGGANG” (where N can be any base) or more generally a strand bias with purines (adenosine ... meiotic double-strand break hotspot which is the primary cause of minisatellite repeat copy number variations ...
Alec Jeffreys - Career - DNA Profiling
... DNA profiling based on typing individual highly variable minisatellites in the human genome was also developed by Alec Jeffreys and his team in 1985, with the term DNA fingerprinting being retained for the ... By focussing on just a few of these highly variable minisatellites, DNA profiling made the system more sensitive, more reproducible, and amenable to computer databasing, and soon became the standard forensic DNA ...
Minisatellite - Pathology
... Minisatellites have been associated with chromosome fragile sites and are proximal to a number of recurrent translocation breakpoints ... Some human minisatellites (~1%) have been demonstrated to be hypermutable, with an average mutation rate in the germline higher than 0.5% up to over 20%, making them the most unstable region in the human ... While other genomes (mouse, rat and pig) contain minisatellite-like sequences, none was found to be hypermutable ...