Metaplasia

Metaplasia (Greek: "change in form") is the reversible replacement of one differentiated cell type with another mature differentiated cell type. The change from one type of cell to another may generally be a part of normal maturation process or caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand the new environment, and so they change into another type more suited to the new environment. If the stimulus that caused metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. Metaplasia is not synonymous with dysplasia and is not directly considered carcinogenic. It is also contrasted with heteroplasia, which is the abnormal growth of cytologic and histologic elements without a stimulus.


Read more about MetaplasiaCauses, Significance in Disease, Examples

Other articles related to "metaplasia":

Cellular Adaptation - Metaplasia
... Metaplasia occurs when a differentiated cell of a certain type is replaced by another cell type, which may be less differentiated ... A prominent example of metaplasia involves the changes associated with the respiratory tract in response to inhalation of irritants, such as smog or smoke ...
Glandular Metaplasia
... Glandular metaplasia is a type of metaplasia where irritated tissue converts to a glandular form ...
Gastritis - Causes - Chronic - Metaplasia
... Mucous gland metaplasia, the reversible replacement of differentiated cells, occurs in the setting of severe damage of the gastric glands, which then waste away (at ... Intestinal metaplasia typically begins in response to chronic mucosal injury in the antrum, and may extend to the body ... Intestinal metaplasia is classified histologically as complete or incomplete ...
Metaplasia - Examples
... table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the change Tissue Normal Metaplasia Stimulus Airways ...
Subareolar Abscess - Squamous Metaplasia of Lactiferous Ducts
... Squamous metaplasia of lactiferous ducts - abbreviated SMOLD is a change where the normal double layer cuboid epithelium of the lactiferous ducts is replaced by squamous keratinizing ... to be completely reversible as the classification as metaplasia would suggest ... SMOLD is distinct from squamous metaplasia that may occur in papilomatous hyperplasia ...