LRP6

LRP6

Identifiers Symbols LRP6; ADCAD2 External IDs OMIM: 603507 MGI: 1298218 HomoloGene: 1747 GeneCards: LRP6 Gene

Gene Ontology
Molecular function low-density lipoprotein receptor activity
receptor binding
frizzled binding
protein binding
Wnt-protein binding
kinase inhibitor activity
toxin transporter activity
apolipoprotein binding
protein homodimerization activity
Wnt-activated receptor activity
coreceptor activity involved in Wnt receptor signaling pathway
Cellular component early endosome
endoplasmic reticulum
plasma membrane
caveola
cell surface
integral to membrane
cytoplasmic vesicle
neuronal cell body
receptor complex
synapse
Biological process gastrulation with mouth forming second
neural tube closure
negative regulation of protein phosphorylation
heart looping
positive regulation of mesenchymal cell proliferation
pericardium morphogenesis
negative regulation of protein kinase activity
synaptic transmission
embryonic pattern specification
anterior/posterior pattern specification
neural crest formation
neural crest cell differentiation
Wnt receptor signaling pathway
cerebellum morphogenesis
thalamus development
cerebral cortex cell migration
forebrain radial glial cell differentiation
Wnt receptor signaling pathway involved in forebrain neuroblast division
formation of radial glial scaffolds
cerebral cortex development
regulation of ossification
embryonic limb morphogenesis
midbrain development
midbrain-hindbrain boundary development
negative regulation of smooth muscle cell apoptotic process
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
external genitalia morphogenesis
cell migration involved in gastrulation
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of apoptotic process
Wnt receptor signaling pathway involved in dorsal/ventral axis specification
canonical Wnt receptor signaling pathway involved in neural crest cell differentiation
canonical Wnt receptor signaling pathway involved in regulation of cell proliferation
regulation of fat cell differentiation
negative regulation of fat cell differentiation
positive regulation of ossification
positive regulation of bone resorption
positive regulation of cell cycle
positive regulation of transcription, DNA-dependent
positive regulation of transcription from RNA polymerase II promoter
bone remodeling
embryonic camera-type eye morphogenesis
negative regulation of epithelial cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
response to folic acid
palate development
convergent extension
embryonic retina morphogenesis in camera-type eye
canonical Wnt receptor signaling pathway
regulation of cell development
face morphogenesis
bone morphogenesis
branching involved in mammary gland duct morphogenesis
trachea cartilage morphogenesis
mammary placode formation
canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development
canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
cellular response to cholesterol
dopaminergic neuron differentiation
negative regulation of protein serine/threonine kinase activity
primitive streak formation
receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
Wnt receptor signaling pathway involved in somitogenesis
axis elongation involved in somitogenesis
positive regulation of canonical Wnt receptor signaling pathway
positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
negative regulation of planar cell polarity pathway involved in neural tube closure
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4040 16974 Ensembl ENSG00000070018 ENSMUSG00000030201 UniProt O75581 O88572 RefSeq (mRNA) NM_002336 NM_008514 RefSeq (protein) NP_002327 NP_032540 Location (UCSC) Chr 12:
12.27 – 12.42 Mb Chr 6:
134.45 – 134.57 Mb PubMed search

Low-density lipoprotein receptor-related protein 6 is a protein that in humans is encoded by the LRP6 gene.

Read more about LRP6:  Interactions

Other articles related to "lrp6":

LRP6 - Interactions
... LRP6 has been shown to interact with DKK1. ...