Junin Virus

Junin Virus

The Junin virus virion is enveloped with a variable diameter of between 50 and 300 nm. The surface of the particle encompasses a layer of T-shaped glycoprotein extensions, extending up to 10 nm from the envelope, which are important for mediating attachment and entry into host cells.

The Junin virus genome comprises two single stranded RNA molecules, each encoding two different genes in an ambisense orientation. The two segments are termed 'short (S)' and 'long (L)' due to their respective lengths. The short segment (around 3400 nucleotides in length) encodes the nucleocapsid protein and the glycoprotein precursor (GPC). The GPC is subsequently cleaved to form two viral glycoproteins, GP1 and GP2 which ultimately form the T-shaped glycoprotein spike which extends from the viral envelope. . The long segment (around 7200 nucleotides in length) encodes the viral polymerase and a zinc binding protein. It is spread by rodents

Read more about Junin VirusEpidemiology and Disease

Other articles related to "junin virus":

Junin Virus - Epidemiology and Disease
... A member of the genus Arenavirus, Junin virus characteristically causes Argentine hemorrhagic fever (AHF) ... Since the discovery of the Junin virus in 1958, the geographical distribution of the pathogen, although still confined to Argentina, has risen ... At the time of discovery, Junin virus was confined to an area of around 15,000 kmĀ² ...

Famous quotes containing the word virus:

    Freedom is the most contagious virus known to man.
    Hubert H. Humphrey (1911–1978)