HMGA

HMGA is a family of high mobility group proteins characterized by an AT-hook. They code for a "small, nonhistone, chromatin-associated protein that has no intrinsic transcriptional activity but can modulate transcription by altering the chromatin architecture". A recent study has shown variations in HMGA2 to have a moderate association with adult height.

Other articles related to "hmga":

List Of Me SH Codes (D12.776) - MeSH D12.776.664 -- Nucleoproteins - MeSH D12.776.664.235 -- Chromosomal Proteins, Non-histone - MeSH D12.776.664.235.400 -- High Mobility Group Proteins
... hmgn2 protein MeSH D12.776.664.235.400.500 -- hmga proteins MeSH D12.776.664.235.400.500.100 -- hmga1a protein MeSH D12.776.664.235.400.500.200 -- hmga1b protein MeSH D12.776.664.235.400.500.300 -- hmga1c ...
HMGA2 - Function
... The expression of HMGA2 in adult tissues is commonly associated with both malignant and benign tumor formation, as well as certain characteristic cancer-promoting mutations ... Homologous proteins with highly conserved sequences are found in other mammalian species, including lab mice (Mus musculus) ...
HMGA1
... characteristic for the HMG family comprising HMGA, HMGB and HMGN proteins ... and no acidic tail is in discussion to be a real member of the HMGA family ...