Guanine Nucleotide Exchange Factor

Guanine Nucleotide Exchange Factor

Guanine nucleotide exchange factors (GEFs) activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP). A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity. Some GEFs can activate multiple GTPases while others are specific to a single GTPase.

Read more about Guanine Nucleotide Exchange Factor:  Function, Mechanism, Structure and Specificity, Regulation, GEFs and Cancer, Examples of GEFs

Other articles related to "nucleotide, nucleotide exchange factor, factors, guanine, exchange, guanine nucleotide exchange factor, factor, nucleotides":

Single-base Extension
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... eIF-2b is a eukaryotic initiation factor necessary to initiate protein translation ... that allows the GPCR to activate an associated GTPase RCC1 is the guanine nucletoot change factor for Ran GTPase ...
Sequential Walking
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