Glycoprotein IX

Identifiers Symbols GP9; CD42a; GPIX External IDs OMIM: 173515 MGI: 1860137 HomoloGene: 144 GeneCards: GP9 Gene

Gene Ontology
Molecular function protein binding
Cellular component plasma membrane
integral to plasma membrane
Biological process cell adhesion
blood coagulation
blood coagulation, intrinsic pathway
platelet activation
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2815 54368 Ensembl ENSG00000169704 ENSMUSG00000030054 UniProt P14770 O88186 RefSeq (mRNA) NM_000174 NM_018762 RefSeq (protein) NP_000165 NP_061232 Location (UCSC) Chr 3:
128.78 – 128.78 Mb Chr 6:
87.78 – 87.78 Mb PubMed search

Glycoprotein IX (platelet) (GP9) also known as CD42a (Cluster of Differentiation 42a), is a human gene.

Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor (VWF; MIM 193400). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V (GP5; MIM 173511).

Other articles related to "glycoprotein":

List Of Human Clusters Of Differentiation
... L (ITGAL), the alpha subunit of LFA-1, a membrane glycoprotein that provides cell-cell adhesion by interaction with ICAM-1 CD11b Integrin Alpha M (ITGAM), the alpha subunit ... CD24 a glycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. 1 (C3b/C4b receptor) CD36 Platelet glycoprotein IV or IIIb (GP IV / GP IIIb) CD37 A leucocyte restricted tetraspanin expressed primarily in B cells, but also found on T cells, Monocytes and Granulocytes ...