Dlbcl

Some articles on dlbcl:

Diffuse Large B Cell Lymphoma
... Diffuse large B-cell lymphoma (DLBCL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies ... DLBCL is an aggressive tumour which can arise in virtually any part of the body, and the first sign of this illness is typically the observation of a rapidly growing mass, sometimes with associated fever ... Usually DLBCL arises from normal B cells, but it can also represent a transformation of other types of lymphoma or leukaemia ...
Diffuse Large B Cell Lymphoma - Classification
... the patient has certain other illnesses related to DLBCL ... a tumour may share many features with both DLBCL and Burkitt lymphoma ... A similar situation can arise between DLBCL and Hodgkin’s lymphoma the tumour is then classified as “B-cell lymphoma, unclassifiable, with features ...
Diffuse Large B Cell Lymphoma - Classification - Gene Expression
... studies have also attempted to distinguish heterogeneous groups of DLBCL from each other ... simultaneously using a DNA microarray, looking for patterns which may help in grouping cases of DLBCL ... Many studies now suggest that cases of DLBCL, NOS can be separated into two groups on the basis of their gene expression profiles these groups are known as germinal centre B-cell-like (GCB) and activated B-cell-like (AB ...
Diffuse Large B Cell Lymphoma - Classification - Immunohistochemistry
... success of gene expression profiling in separating biologically distinct cases of DLBCL, NOS, some researchers examined whether a similar distinction could be made using ... genes which had been implicated in DLBCL gene expression studies ... Several algorithms for separating DLBCL cases by IHC arose out of this research, categorizing tissue samples into groups most commonly known as GCB and non-GCB ...