CD117 - Mobilization


Hematopoietic progenitor cells are normally present in the blood at low levels. Mobilization is the process by which progenitors are made to migrate from the bone marrow into the bloodstream, thus increasing their numbers in the blood. Mobilization is used clinically as a source of hematopoietic stem cells for hematopoietic stem cell transplantation (HSCT). Signaling through CD117 has been implicated in mobilization. At the current time, G-CSF is the main drug used for mobilization. G-CSF indirectly activates CD117. Direct CD117 agonists are currently being developed as mobilization agents.

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Other articles related to "mobilization":

British Mandate For Palestine - History of Palestine Under The British Mandate - World War II - Mobilization
... From Palestine Regiment, two platoons, one Jewish, under the command of Brigadier Ernest Benjamin, and another Arab were sent to join allied forces on the Italian Front, having taken part of final offensive there ... Besides Jews and Arabs from Palestine, in total by mid-1944 the British had assembled a multiethnic force consisting of volunteers European Jewish (refugees from German-occupied countries), Yeminites and Abyssinian Jews. ...
Minutemen - American Revolutionary War Period
... in Worcester met and came up with a new militia mobilization plan in their County Convention ... local government officials that the "Minuteman" mobilization scheme worked well ... The events on April 19, 1775 proved them wrong when the mobilization fielded large numbers of minutemen to confront them at Concord that, with the arrival of the ...
The M109A3GN Programme
... Most of these were assigned as mobilization reserve and went to several mobilization storage facilities ... With the end of the Cold War, mobilization storages lost their importance, and the amount of M109 howitzers were drastically reduced to 56 ...
Economic Mobilization
... Economic mobilization is the preparation of resources for usage in a national emergency by carrying out changes in the organization of the national economy ...

Famous quotes containing the word mobilization:

    When they are preparing for war, those who rule by force speak most copiously about peace until they have completed the mobilization process.
    Stefan Zweig (18811942)