CAMK4

Identifiers Symbols CAMK4; CaMK IV; CaMK-GR; IV; caMK External IDs OMIM: 114080 MGI: 88258 HomoloGene: 100780 ChEMBL: 2494 GeneCards: CAMK4 Gene EC number 2.7.11.17

Gene Ontology
Molecular function calmodulin-dependent protein kinase activity
calmodulin binding
ATP binding
Cellular component nucleus
nucleoplasm
nucleolus
cytosol
Biological process myeloid dendritic cell cytokine production
protein phosphorylation
nucleocytoplasmic transport
inflammatory response
signal transduction
epidermal growth factor receptor signaling pathway
activation of phospholipase C activity
synaptic transmission
neuron-neuron synaptic transmission
long-term memory
fibroblast growth factor receptor signaling pathway
regulation of T cell differentiation in thymus
myeloid dendritic cell differentiation
regulation of osteoclast differentiation
positive regulation of transcription, DNA-dependent
positive regulation of protein export from nucleus
nerve growth factor receptor signaling pathway
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 814 12326 Ensembl ENSG00000152495 ENSMUSG00000038128 UniProt Q16566 P08414 RefSeq (mRNA) NM_001744 NM_009793 RefSeq (protein) NP_001735 NP_033923 Location (UCSC) Chr 5:
110.56 – 110.83 Mb Chr 18:
32.94 – 33.2 Mb PubMed search

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.