Cacna

Some articles on :

Cav1.4
... This gene encodes a member of the alpha-1 subunit family a protein in the voltage-dependent calcium channel complex ... Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1111 ratio ...
Voltage-dependent Calcium Channel - Channel Subunits - α2δ Subunit
... The α2δ-1 and α2δ-2 subunits are the binding site for at least two anticonvulsant drugs, gabapentin (Neurontin) and pregabalin (Lyrica), that also find use in treating chronic neuropathic pain. ...