Arhgef

Some articles on arhgef:

ARHGEF1
... Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors ... The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals ...
ARHGEF9
... ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state ... These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling ...
ARHGEF6
... Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors ... The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP ...
ARHGEF4 - Model Organisms
... Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion ... Twenty two tests were carried out on homozygous mutant mice and one significant abnormality was observed males has atypical peripheral blood lymphocyte parameters, including a decreased B cell number and an increased granulocyte number ...