Amelogenesis

Amelogenesis is the formation of enamel on teeth and occurs during the crown stage of tooth development after dentinogenesis, which is the formation of dentine. Although dentine must be present for enamel to be formed, it is also true that ameloblasts must be present in order for dentinogenesis to continue. A message is sent from the newly differentiated odontoblasts to the inner enamel epithelium (IEE), causing the epithelial cells to further differentiate into active secretory ameloblasts. Dentinogenesis is in turn dependent on signals from the differentiating IEE in order for the process to continue. This prerequisite is an example of the biological concept known as reciprocal induction, in this instance between mesenchymal and epithelial cells.

Amelogenesis is considered to have two stages. The first stage is known as the secretory phase, and the second stage is known as the maturation stage. Proteins and an organic matrix form a partially mineralized enamel in the secretory stage. The maturation stage completes enamel mineralization.

Other articles related to "amelogenesis":

Amelogenesis Imperfecta
... Amelogenesis imperfecta presents with abnormal formation of the enamel or external layer of teeth ... Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel ameloblastin, enamelin, tuftelin and amelogenin ... People afflicted with amelogenesis imperfecta have teeth with abnormal color yellow, brown or grey ...
Amelogenesis - Stages - Maturation Stage
... Enamel mineralisation only occurs once (as ameloblasts die out) therefore after amelogenesis, enamel is final ...
Amelogenesis Imperfecta - Genetics
... in the AMELX, ENAM, MMP20, and KLK-4 genes have been found to cause amelogenesis imperfecta (non-syndromic form) ... looking for mutations in other genes that may also cause amelogenesis imperfecta. 15q21.3 AI3 130900 FAM83H 8q24.3 AIH1 301200 AMELX Xp22.3-p22.1 Amelogenesis imperfecta can have different inheritance patterns depending on the gene that is altered ...
List Of Diseases (A) - Am - Ama–Amy
... Amelia facial dysmorphism Amelia X linked Amelogenesis Amelogenesis Imperfecta hypomaturation type Amelogenesis imperfecta local hypoplastic form Amelogenesis imperfecta ...