LimitationsSee also: Resolution (electron density)
As the crystal's repeating unit, its unit cell, becomes larger and more complex, the atomic-level picture provided by X-ray crystallography becomes less well-resolved (more "fuzzy") for a given number of observed reflections. Two limiting cases of X-ray crystallography—"small-molecule" and "macromolecular" crystallography—are often discerned. Small-molecule crystallography typically involves crystals with fewer than 100 atoms in their asymmetric unit; such crystal structures are usually so well resolved that the atoms can be discerned as isolated "blobs" of electron density. By contrast, macromolecular crystallography often involves tens of thousands of atoms in the unit cell. Such crystal structures are generally less well-resolved (more "smeared out"); the atoms and chemical bonds appear as tubes of electron density, rather than as isolated atoms. In general, small molecules are also easier to crystallize than macromolecules; however, X-ray crystallography has proven possible even for viruses with hundreds of thousands of atoms.
Other articles related to "limitations":
... FRMP, Fairness These include Flight Time Limitations (FTL) - Daily, Weekly, Monthly, Quarterly and Yearly Flight Duty Period Limitations (FDP) - Daily, Weekly, Monthly Duty Period Limitations - Daily, Weekly ... Separation of assignments, base allocation of crew members, Reserve limitations, Crew Training Requirements ...
... Due to the limitations of the CD-i, several features could not be included in the game, such as large numbers of sprites on the screen, Mode 7 and many visual ...
... asserted that limitations on rights must be motivated by an objective of sufficient importance ...
... Several publications have commented on limitations given to pre-release reviewers by Konami, including discussion on the length of cutscenes and size of the PS3 ... These limitations resulted in Electronic Gaming Monthly delaying its review ... Konami have withheld review code because of non-compliance with the limitations ...
Famous quotes containing the word limitations:
“The motion picture made in Hollywood, if it is to create art at all, must do so within such strangling limitations of subject and treatment that it is a blind wonder it ever achieves any distinction beyond the purely mechanical slickness of a glass and chromium bathroom.”
—Raymond Chandler (18881959)
“Much of what contrives to create critical moments in parenting stems from a fundamental misunderstanding as to what the child is capable of at any given age. If a parent misjudges a childs limitations as well as his own abilities, the potential exists for unreasonable expectations, frustration, disappointment and an unrealistic belief that what the child really needs is to be punished.”
—Lawrence Balter (20th century)
“Growing up means letting go of the dearest megalomaniacal dreams of our childhood. Growing up means knowing they cant be fulfilled. Growing up means gaining the wisdom and skills to get what we want within the limitations imposed by realitya reality which consists of diminished powers, restricted freedoms and, with the people we love, imperfect connections.”
—Judith Viorst (20th century)