William Andrew Wallace (November 28, 1827 – May 22, 1896) was an American lawyer and Democratic party politician from Clearfield, Pennsylvania. He served in the Pennsylvania State Senate and was its speaker in 1871. He represented Pennsylvania in the United States Senate from 1875 to 1881.
After his U.S. Senate service Wallace was returned to the state senate. In later years he became interested in developing local coal resources and headed the Beech Creek Railroad.
Wallace died while was in New York City on business in 1896. He was returned to Clearfield and buried in the Hillcrest Cemetery.