Genetic recombination is the breaking and rejoining of DNA strands to form new molecules of DNA encoding a novel set of genetic information. Recombination can occur between similar molecules of DNA, as in the homologous recombination of chromosomal crossover, or dissimilar molecules, as in non-homologous end joining. V(D)J recombination in organisms with an adaptive immune system is a type of genetic recombination that helps immune cells rapidly diversify to recognize and adapt to new pathogens. Recombination is a common method of DNA repair in both bacteria and eukaryotes.
Read more about Genetic Recombination.
Some articles on genetic recombination:
... In genetic engineering, recombination can also refer to artificial and deliberate recombination of disparate pieces of DNA, often from different organisms, creating what is called ... A prime example of such a use of genetic recombination is gene targeting, which can be used to add, delete or otherwise change an organism's genes ... Techniques based on genetic recombination are also applied in protein engineering to develop new proteins of biological interest ...
... that is thought to mediate chromosome pairing, synapsis, and recombination (crossing-over) ... It is now evident that the synaptonemal complex is not required for genetic recombination ... Research has shown that not only does it form after genetic recombination but mutant yeast cells unable to assemble a synaptonemal complex can still engage in the exchange of genetic information ...
... Because genetic recombination between two markers is detected only if there are an odd number of chromosomal crossovers between the two markers, the distance in ... the number of chromosomal crossovers is according to a Poisson distribution, a genetic distance of centimorgans will lead to an odd number of chromosomal crossovers, and hence a ... can be calculated directely using The probability of recombination is approximately for small values of and approaches 50% as goes to infinity ...
Famous quotes containing the word genetic:
“Nature, we are starting to realize, is every bit as important as nurture. Genetic influences, brain chemistry, and neurological development contribute strongly to who we are as children and what we become as adults. For example, tendencies to excessive worrying or timidity, leadership qualities, risk taking, obedience to authority, all appear to have a constitutional aspect.”
—Stanley Turecki (20th century)