What is folic acid?

Folic Acid

Folic acid (also known as folate, vitamin M, vitamin B9, vitamin Bc (or folacin), pteroyl-L-glutamic acid, pteroyl-L-glutamate, and pteroylmonoglutamic acid) are forms of the water-soluble vitamin B9. Folic acid is itself not biologically active, but its biological importance is due to tetrahydrofolate and other derivatives after its conversion to dihydrofolic acid in the liver.

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Some articles on folic acid:

MOMS Study - Pathophysiology
... Research has shown the lack of folic acid (folate) is a contributing factor in the pathogenesis of neural tube defects, including spina bifida ... It is unknown how or why folic acid has this effect ... to about 1% if the woman takes high doses (4 mg/day) of folic acid before and during pregnancy ...
MOMS Study - Prevention
... However, dietary supplementation with folic acid has been shown to be helpful in reducing the incidence of spina bifida ... Sources of folic acid include whole grains, fortified breakfast cereals, dried beans, leaf vegetables and fruits ... Public Health Agency of Canada and UK recommended amount of folic acid for women of childbearing age and women planning to become pregnant is at least 0.4 mg/day of folic ...
Folic Acid - Dietary Fortification - United States
... dietary supplements and 35% uses dietary supplements containing folic acid ... The age group consuming the most folate and folic acid is the >50 group ... States Food and Drug Administration (FDA) published regulations requiring the addition of folic acid to enriched breads, cereals, flours, corn meals, pastas, rice, and other grain products ...
Levomefolic Acid
... Levomefolic acid (INN) (also known as 5-MTHF, l-methylfolate and 5-methyltetrahydrofolate) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the ... The un-methylated form, folic acid (vitamin B9), is a synthetic form of folate found in nutritional supplements ... Synthetic folic acid is metabolized in the body into levomefolic acid ...
Pyrimethamine - Clinical Use
... given with a sulfonamide and folinic acid sulfonamides inhibit dihydropteroate synthetase, an enzyme that participates in folic acid synthesis from para-aminobe ... work synergistically with pyrimethamine by blocking a different enzyme needed for folic acid synthesis ... folinic acid (leucovorin) is a folic acid derivative that is converted to tetrahydrofolate (the primary active form of folic acid) in vivo without relying on dihydrofolate reductase ...