What is epoxide?

Epoxide

An epoxide is a cyclic ether with three ring atoms. This ring approximately defines an equilateral triangle, which makes it highly strained. The strained ring makes epoxides more reactive than other ethers. Simple epoxides are named from the parent compound ethylene oxide or oxirane, such as in chloromethyloxirane. As a functional group, epoxides feature the epoxy prefix, such as in the compound 1,2-epoxycycloheptane, which can also be called cycloheptene epoxide, or simply cycloheptene oxide.

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Some articles on epoxide:

Epoxide - Perepoxides
... Perepoxides are epoxides with an additional oxygen atom attached to the epoxide-oxygen ...
Soluble Epoxide Hydrolase - Discovery
... sEH was first identified in the cytosolic fraction of mouse liver through its activity on epoxide containing substrates such as juvenile hormone and lipid ... The soluble EH activity was shown to be distinct from that of the microsomal epoxide hydrolase (mEH) previously discovered with a different substrate ... Studies using a lipid epoxide as a substrate detected this activity in the soluble fraction of multiple organs, though at a lesser amount than in liver and kidney ...
Limonene-1,2-epoxide Hydrolase
... In enzymology, a limonene-1,2-epoxide hydrolase (EC 3.3.2.8) is an enzyme that catalyzes the chemical reaction limonene-1,2-epoxide + H2O limonene-1,2-diol Thus, the two substrates of this enzyme are ... The systematic name of this enzyme class is limonene-1,2-epoxide hydrolase ... Epoxide hydrolases catalyse the hydrolysis of epoxides to corresponding diols, which is important in detoxification, synthesis of signal molecules, or metabolism ...
Epoxide Hydrolase
... Epoxide hydrolase (also known as epoxide hydratase) functions in detoxication during drug metabolism ... It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body ... Epoxides result from the degradation of aromatic compounds ...
Kinetic Resolution Reactions Utilizing Synthetic Reagents - Epoxide Openings
... efficient asymmetric synthesis of terminal epoxides, which are key chiral building blocks ... Due to the inexpensiveness of most racemic terminal epoxides and their inability to generally be subjected to classical resolution, an effective kinetic resolution of terminal epoxides would serve as a highly ... In 1996, Jacobsen and coworkers developed a methodology for the kinetic resolution of epoxides via nucleophilic ring-opening with attack by an azide anion ...