What is diazepam?

  • (noun): A tranquilizer (trade name Valium) used to relieve anxiety and relax muscles; acts by enhancing the inhibitory actions of the neurotransmitter GABA; can also be used as an anticonvulsant drug in cases of nerve agent poisoning.
    Synonyms: Valium


Diazepam ( /daɪˈæzɨpæm/), first marketed as Valium ( /ˈvæliəm/) by Hoffmann-La Roche, is a benzodiazepine drug. Diazepam is also marketed in Australia as Antenex. It is commonly used for treating anxiety, insomnia, seizures including status epilepticus, muscle spasms (such as in cases of tetanus), restless legs syndrome, alcohol withdrawal, benzodiazepine withdrawal and Ménière's disease. It may also be used before certain medical procedures (such as endoscopies) to reduce tension and anxiety, and in some surgical procedures to induce amnesia. It possesses anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. The pharmacological action of diazepam enhances the effect of the neurotransmitter GABA by binding to the benzodiazepine site on the GABAA receptor (via the constituent chlorine atom) leading to central nervous system depression.

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Some articles on diazepam:

Diazepam - Veterinary Uses
... Diazepam is used as a short-term sedative and anxiolytic for cats and dogs ... It is also used for short-term treatment of seizures in dogs and short-term and long-term treatment of seizures in cats ...
Long-term Effects Of Benzodiazepines - Symptoms - Immune System
... Diazepam and clonazepam have been found to have long-lasting, but not permanent, immunotoxic effects in the fetus of pregnant rats ... However, single very high doses of diazepam have been found to cause lifelong immunosuppression in neonatal rats ... No studies have been done to assess the immunotoxic effects of diazepam in humans however, high prescribed doses of diazepam, in humans, has been found to be a major risk of ...
Loprazolam - Side Effects
... Side effects of loprazolam are generally the same as for other benzodiazepines such as diazepam ... The only main difference in side effects of loprazolam and diazepam is it is less prone to day time sedation as the half-life of loprazolam is considered to be intermediate whereas ...
... Avizafone (Pro-Diazepam) is a water-soluble prodrug of diazepam ... enzymes in the blood to form the active drug diazepam ...
Premazepam - Properties
... similar psychological test results to those produced by diazepam ... initial dosing with premazepam produces similar sedative effects as compared with diazepam, although psychomotor impairments are greater with premazepam than with diazepam ... for more than one day premazepam causes less sedation and less psychomotor impairment than diazepam ...